Comprehensive Guide to Reporting Animal Research

Originally published in PLOS Biology, ARRIVE was developed by the National Centre for the Replacement Refinement & Reduction of Animals in Research (NC3Rs). The guidelines were made in consultation with the global scientific research community. In 2020, they were revised to create ARRIVE 2.0, which splits the checklist items into the ARRIVE Essential 10 and Recommended Set. At the ARRIVE website you will find extensive resources for helping biomedical researchers ensure comprehensive reports of experimental design and results. 

Experimental Physiology 2010 95:842-844 doi:10.1113/expphysiol.2010.053793 PMID:20610776

J Pharmacol Pharmacother. 2010;1(2):94-99. PMID: 21350617

Journal of Cerebral Blood Flow & Metabolism 31:991-993 doi:10.1038/jcbfm.2010.220, PMC3070981

• Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M., & Altman, D. G. (2010). Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research.

• Kilkenny C, Browne WJ, Cuthill IC et al. (2014). Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. Animals 4(1):35-44 doi:10.3390/ani4010035

1. Upload your manuscript.
2. Highlight the text that corresponds to the items.
3. Download the completed checklist.
4. Submit it with your manuscript.

If a checklist item does not apply to your study, state your reason for not reporting this information in the right-hand column. A completed checklist can provide supplementary information and help ensure reviewers and editors high-quality reporting.


Reach Out to Us

For more information on our collection of research reporting protocols, contact our team at Meridian Network. We look forward to hearing from you.